Train: Trenitalia or Trenitalia Regionale
Direct Trenitalia trains to Pisa Centrale leave from Roma Termini and, for a few departures, from Roma Ostiense; depending on the train type (Regionale Veloce, Intercity, Frecciargento, Frecciabianca) the ride takes between about two and a half and a little over three hours. For a day trip only the early departures count: there is a small cluster of direct trains around dawn, then a gap until mid morning, and taking a later train cuts your time in Pisa roughly in half. Buy your tickets from Trenitalia before you travel; the Frecce require a reserved seat on a specific train, and fares are dynamic, so booking early is usually cheaper. Some connections, especially on the way back, are not direct and involve a change, often at Empoli or Firenze Santa Maria Novella; if you book one of those, leave yourself a comfortable connection time.
- Operator
- Trenitalia or Trenitalia Regionale
- Route
- Roma Ostiense → Pisa Centrale
- Journey time
- 3 h 16 min
- Morning departures
- Monday and Friday: 2 departures; Tuesday to Thursday and Saturday to Sunday: 1 departure
- Travel fare
- Outward €26.35; return €26.35 (€52.70 return total)











